Seth McFarlane + Flintstones = OH F**K NO!
OK maybe I'm old school, having grown up when the original series was on the air. But McFarlane is the LAST person on earth I would want to see doing an "update" of the franchise. There are some things that if you tried to change what they are, they aren't what you started with, not even close. I give you the GINO film as a prime example. Unless I am completely wrong about the talent that exists in Seth McFarlane, this will be nothing but FINO to me.
Now excuse me, I'm going to Netflix and see if they have A Man Called Flintstone.