I'm rather surprised that Cartoon Network has never attemped to reintroduce the Powerpuff Girls here in the US through the show
Powerpuff Girls Z. According to the Wikipedia page besides CN Japan, it has run on CN Australia, India, Philippenes and Boomerang Australia.
Here's part of the first episode in the original Japanese:
http://youtu.be/RvLAwi1MuBY
As PGZ has already ran outside of Japan there's an existing English dub (which can be easily found on Youtube). But I think a new dub is called if Cartoon Network ever releases the show in the US, a new dub that brings back the cast from the original show to reprise their roles.
Although, I suppose I can't be too surprised -- after all the executives did approve that annoying orange show...