I saw it opening weekend and it was a lot more fun than On Stranger Tides. I was actually surprised at how much I liked this one, but I think I was just going in with super low expectations. Javier was a fantastic villain and I think that's what elevates this to being better what what I thought the 5th movie of the series would be. Although I feel like David Wenham was wasted in this movie.
The main issue with this movie, and I think the series as it has gone on, is that Jack started out a character who acted up his craziness to hide his intelligence. But he is now just a drunken Mr. Magoo, winning the day less out of clever plans and more out of sheer luck and happenstance. Like a drunken Mr. Magoo.
So as much as I like the series, unless they refocus or reboot (But Depp still draw crowds) I don't think there will be a 6th or at least a good 6th.